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Screening for Active Compounds Targeting Human Natural Killer Cell Activation Identifying Daphnetin as an Enhancer for IFN-γ Production and Direct Cytotoxicity

Natural killer (NK) cells are a potent weapon against tumor and viral infection. Finding active compounds with the capacity of enhancing NK cell effector functions will be effective to develop new anti-cancer drugs. In this study, we initially screened 287 commercially available active compounds by...

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Detalles Bibliográficos
Autores principales: Yao, Baige, Yang, Qinglan, Yang, Yao, Li, Yana, Peng, Hongyan, Wu, Shuting, Wang, Lili, Zhang, Shuju, Huang, Minghui, Wang, Erqiang, Xiong, Peiwen, Luo, Ting, Li, Liping, Jia, Sujie, Deng, Yafei, Deng, Youcai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8693168/
https://www.ncbi.nlm.nih.gov/pubmed/34956168
http://dx.doi.org/10.3389/fimmu.2021.680611