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Screening for Active Compounds Targeting Human Natural Killer Cell Activation Identifying Daphnetin as an Enhancer for IFN-γ Production and Direct Cytotoxicity
Natural killer (NK) cells are a potent weapon against tumor and viral infection. Finding active compounds with the capacity of enhancing NK cell effector functions will be effective to develop new anti-cancer drugs. In this study, we initially screened 287 commercially available active compounds by...
Autores principales: | Yao, Baige, Yang, Qinglan, Yang, Yao, Li, Yana, Peng, Hongyan, Wu, Shuting, Wang, Lili, Zhang, Shuju, Huang, Minghui, Wang, Erqiang, Xiong, Peiwen, Luo, Ting, Li, Liping, Jia, Sujie, Deng, Yafei, Deng, Youcai |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8693168/ https://www.ncbi.nlm.nih.gov/pubmed/34956168 http://dx.doi.org/10.3389/fimmu.2021.680611 |
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