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Tuning Receptor Properties of Metal–Amyloid Beta Complexes. Studies on the Interaction between Ni(II)–Aβ(5–9) and Phosphates/Nucleotides

[Image: see text] Amyloid-beta (Aβ) peptides, potentially relevant in the pathology of Alzheimer’s disease, possess distinctive coordination properties, enabling an effective binding of transition-metal ions, with a preference for Cu(II). In this work, we found that a N-truncated Aβ analogue bearing...

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Detalles Bibliográficos
Autores principales: Tobolska, Aleksandra, Wezynfeld, Nina E., Wawrzyniak, Urszula E., Bal, Wojciech, Wróblewski, Wojciech
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8693174/
https://www.ncbi.nlm.nih.gov/pubmed/34878265
http://dx.doi.org/10.1021/acs.inorgchem.1c03285