Cargando…
Tuning Receptor Properties of Metal–Amyloid Beta Complexes. Studies on the Interaction between Ni(II)–Aβ(5–9) and Phosphates/Nucleotides
[Image: see text] Amyloid-beta (Aβ) peptides, potentially relevant in the pathology of Alzheimer’s disease, possess distinctive coordination properties, enabling an effective binding of transition-metal ions, with a preference for Cu(II). In this work, we found that a N-truncated Aβ analogue bearing...
Autores principales: | Tobolska, Aleksandra, Wezynfeld, Nina E., Wawrzyniak, Urszula E., Bal, Wojciech, Wróblewski, Wojciech |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2021
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8693174/ https://www.ncbi.nlm.nih.gov/pubmed/34878265 http://dx.doi.org/10.1021/acs.inorgchem.1c03285 |
Ejemplares similares
-
Aβ(5–x) Peptides:
N-Terminal Truncation Yields Tunable Cu(II) Complexes
por: Wezynfeld, Nina E., et al.
Publicado: (2020) -
Ni(II) Ions May Target the Entire Melatonin Biosynthesis Pathway—A Plausible Mechanism of Nickel Toxicity
por: Wezynfeld, Nina E., et al.
Publicado: (2022) -
Copper Transporters? Glutathione Reactivity of Products
of Cu–Aβ Digestion by Neprilysin
por: Stefaniak, Ewelina, et al.
Publicado: (2020) -
Intermediate Cu(II)-Thiolate Species in the Reduction
of Cu(II)GHK by Glutathione: A Handy Chelate for Biological Cu(II)
Reduction
por: Ufnalska, Iwona, et al.
Publicado: (2021) -
Redox Activity of Copper(II) Complexes with NSFRY Pentapeptide and Its Analogues
por: Wiloch, Magdalena Zofia, et al.
Publicado: (2016)