Cargando…

Gut microbiota-based vaccination engages innate immunity to improve blood glucose control in obese mice

OBJECTIVE: Obesity and diabetes increase circulating levels of microbial components derived from the gut microbiota. Individual bacterial factors (i.e., postbiotics) can have opposing effects on blood glucose. METHODS: We tested the net effect of gut bacterial extracts on blood glucose in mice using...

Descripción completa

Detalles Bibliográficos
Autores principales:	Duggan, Brittany M., Tamrakar, Akhilesh K., Barra, Nicole G., Anhê, Fernando F., Paniccia, Gabriella, Wallace, Jessica G., Stacey, Hannah D., Surette, Michael G., Miller, Matthew S., Sloboda, Deborah M., Schertzer, Jonathan D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8693341/ https://www.ncbi.nlm.nih.gov/pubmed/34839023 http://dx.doi.org/10.1016/j.molmet.2021.101404

Ejemplares similares

Human gut microbiota after bariatric surgery alters intestinal morphology and glucose absorption in mice independently of obesity
por: Anhê, Fernando F, et al.
Publicado: (2023)

Postbiotics engage IRF4 in adipocytes to promote sex‐dependent changes in blood glucose during obesity
por: Duggan, Brittany M., et al.
Publicado: (2022)

The murine female intestinal microbiota does not shift throughout the estrous cycle
por: Wallace, Jessica G., et al.
Publicado: (2018)

Inflammation promotes adipocyte lipolysis via IRE1 kinase
por: Foley, Kevin P., et al.
Publicado: (2021)

Tyrosine kinase inhibitors of Ripk2 attenuate bacterial cell wall-mediated lipolysis, inflammation and dysglycemia
por: Duggan, Brittany M., et al.
Publicado: (2017)

Gut microbiota impairs insulin clearance in obese mice
por: Foley, Kevin P., et al.
Publicado: (2020)

NOD1 Activators Link Innate Immunity to Insulin Resistance
por: Schertzer, Jonathan D., et al.
Publicado: (2011)

The intestine and the microbiota in maternal glucose homeostasis during pregnancy
por: Yeo, Erica, et al.
Publicado: (2022)

Obesity during pregnancy results in maternal intestinal inflammation, placental hypoxia, and alters fetal glucose metabolism at mid-gestation
por: Wallace, Jessica G., et al.
Publicado: (2019)

Determining the metabolic impact of postbiotics in mice
por: Anhê, Fernando F., et al.
Publicado: (2022)

Parity modulates impact of BMI and gestational weight gain on gut microbiota in human pregnancy
por: Kennedy, Katherine M., et al.
Publicado: (2023)

Long term but not short term exposure to obesity related microbiota promotes host insulin resistance
por: Foley, Kevin P., et al.
Publicado: (2018)

Life‐long exercise training and inherited aerobic endurance capacity produce converging gut microbiome signatures in rodents
por: Anhê, Fernando F., et al.
Publicado: (2022)

Lower brown adipose tissue activity is associated with non-alcoholic fatty liver disease but not changes in the gut microbiota
por: Ahmed, Basma A., et al.
Publicado: (2021)

Intestinal permeability and peripheral immune cell composition are altered by pregnancy and adiposity at mid- and late-gestation in the mouse
por: Ribeiro, Tatiane A., et al.
Publicado: (2023)

A comparison of intestinal microbiota in a population of low-risk infants exposed and not exposed to intrapartum antibiotics: The Baby & Microbiota of the Intestine cohort study protocol
por: Simioni, Julia, et al.
Publicado: (2016)

Muc2 Mucin and Nonmucin Microbiota Confer Distinct Innate Host Defense in Disease Susceptibility and Colonic Injury
por: Leon-Coria, Aralia, et al.
Publicado: (2020)

Bacterial Postbiotics as Promising Tools to Mitigate Cardiometabolic Diseases
por: Anhê, Fernando F., et al.
Publicado: (2021)

Intestinal Microbiota Contributes to Energy Balance, Metabolic Inflammation, and Insulin Resistance in Obesity
por: Cavallari, Joseph F., et al.
Publicado: (2017)

Azithromycin and the microbiota of cystic fibrosis sputum
por: Acosta, Nicole, et al.
Publicado: (2021)

Adhesion of Diarrheagenic Escherichia coli and Inhibition by Glycocompounds Engaged in the Mucosal Innate Immunity
por: Pereira, Alex L., et al.
Publicado: (2013)

Targeting macrophage scavenger receptor 1 promotes insulin resistance in obese male mice
por: Cavallari, Joseph F., et al.
Publicado: (2018)

Longitudinal sampling of the lung microbiota in individuals with cystic fibrosis
por: Whelan, Fiona J., et al.
Publicado: (2017)

Iron Reshapes the Gut Microbiome and Host Metabolism
por: Botta, Amy, et al.
Publicado: (2021)

TNF, but not hyperinsulinemia or hyperglycemia, is a key driver of obesity‐induced monocytosis revealing that inflammatory monocytes correlate with insulin in obese male mice
por: Breznik, Jessica A., et al.
Publicado: (2018)

Brain microbiota disruption within inflammatory demyelinating lesions in multiple sclerosis
por: Branton, W. G., et al.
Publicado: (2016)

Computer-Aided Drug Design of Natural Candidates for the Treatment of Non-Communicable Diseases
por: Zaid, Hilal, et al.
Publicado: (2022)

Responsiveness of the innate immune system and glucose concentrations in the oldest old
por: Wijsman, Carolien A., et al.
Publicado: (2011)

High-fructose feeding suppresses cold-stimulated brown adipose tissue glucose uptake independently of changes in thermogenesis and the gut microbiome
por: Richard, Gabriel, et al.
Publicado: (2022)

492: CF innate immune defect affects CF intestinal microbiota
por: Scull, C., et al.
Publicado: (2021)

Engaging the Innate and Adaptive Antitumor Immune Response in Lymphoma
por: Csizmar, Clifford M., et al.
Publicado: (2021)

β-Sitosterol-D-Glucopyranoside Mimics Estrogenic Properties and Stimulates Glucose Utilization in Skeletal Muscle Cells
por: Pandey, Jyotsana, et al.
Publicado: (2021)

Luminal and Mucosal Microbiota of the Cecum and Large Colon of Healthy and Diarrheic Horses
por: Arroyo, Luis G., et al.
Publicado: (2020)

Diabetes and Metabolism Disorders Medicinal Plants: A Glance at the Past and a Look to the Future 2018
por: Zaid, Hilal, et al.
Publicado: (2018)

Interactions between Innate Immunity, Microbiota, and Probiotics
por: Giorgetti, GianMarco, et al.
Publicado: (2015)

Innate lymphoid cells, possible interaction with microbiota
por: Moro, Kazuyo, et al.
Publicado: (2014)

The interplay between innate lymphoid cells and microbiota
por: Wang, Rui, et al.
Publicado: (2023)

Microbiota and Nod-like receptors balance inflammation and metabolism during obesity and diabetes
por: Rodrigues e-Lacerda, Rodrigo, et al.
Publicado: (2023)

Tinosporaside from Tinospora cordifolia Encourages Skeletal Muscle Glucose Transport through Both PI-3-Kinase- and AMPK-Dependent Mechanisms
por: Mishra, Akansha, et al.
Publicado: (2023)

Cryopreservation of Natural Killer Cells Pre-Complexed with Innate Cell Engagers
por: Reusch, Uwe, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_6ma1o1es6ajgoshtke3s9k4nsg