Thank ORP9 for FFAT: With endosomal ORP10, it’s fission accomplished!

Heterogeneity in endosomal membrane phospholipid content is emerging as a regulator of endocytic trafficking pathways. Kawasaki et al. (2021. J. Cell. Biol. https://doi.org/10.1083/jcb.202103141) demonstrate exchange of endosomal PI4P for PS by ORP10 at ER–endosome contact sites, with the consequent...

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Detalles Bibliográficos
Autores principales: Wong, Louise H., Martello, Andrea, Eden, Emily R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Spotlight
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8693358/
https://www.ncbi.nlm.nih.gov/pubmed/34928309
http://dx.doi.org/10.1083/jcb.202112057
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author Wong, Louise H.
Martello, Andrea
Eden, Emily R.
author_facet Wong, Louise H.
Martello, Andrea
Eden, Emily R.
author_sort Wong, Louise H.
collection PubMed
description Heterogeneity in endosomal membrane phospholipid content is emerging as a regulator of endocytic trafficking pathways. Kawasaki et al. (2021. J. Cell. Biol. https://doi.org/10.1083/jcb.202103141) demonstrate exchange of endosomal PI4P for PS by ORP10 at ER–endosome contact sites, with the consequent recruitment of endosomal fission factors.
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spelling pubmed-86933582022-07-03 Thank ORP9 for FFAT: With endosomal ORP10, it’s fission accomplished! Wong, Louise H. Martello, Andrea Eden, Emily R. J Cell Biol Spotlight Heterogeneity in endosomal membrane phospholipid content is emerging as a regulator of endocytic trafficking pathways. Kawasaki et al. (2021. J. Cell. Biol. https://doi.org/10.1083/jcb.202103141) demonstrate exchange of endosomal PI4P for PS by ORP10 at ER–endosome contact sites, with the consequent recruitment of endosomal fission factors. Rockefeller University Press 2021-12-20 /pmc/articles/PMC8693358/ /pubmed/34928309 http://dx.doi.org/10.1083/jcb.202112057 Text en © 2021 Wong et al. https://creativecommons.org/licenses/by-nc-sa/4.0/http://www.rupress.org/terms/This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Spotlight
Wong, Louise H.
Martello, Andrea
Eden, Emily R.
Thank ORP9 for FFAT: With endosomal ORP10, it’s fission accomplished!
title Thank ORP9 for FFAT: With endosomal ORP10, it’s fission accomplished!
title_full Thank ORP9 for FFAT: With endosomal ORP10, it’s fission accomplished!
title_fullStr Thank ORP9 for FFAT: With endosomal ORP10, it’s fission accomplished!
title_full_unstemmed Thank ORP9 for FFAT: With endosomal ORP10, it’s fission accomplished!
title_short Thank ORP9 for FFAT: With endosomal ORP10, it’s fission accomplished!
title_sort thank orp9 for ffat: with endosomal orp10, it’s fission accomplished!
topic Spotlight
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8693358/
https://www.ncbi.nlm.nih.gov/pubmed/34928309
http://dx.doi.org/10.1083/jcb.202112057
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