Band-like hyperintensity along the ventral surface of the brain stem on FLAIR and DWI in leptomeningeal carcinomatosis of lung adenocarcinoma

Since leptomeningeal carcinomatosis is rarely observed before diagnosis of the primary cancer, its detection is often delayed. We report the case of a 60-year-old woman who presented with lung adenocarcinoma with leptomeningeal carcinomatosis. Magnetic resonance imaging showed the characteristic abn...

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Autores principales: Yokota, Hajime, Mukai, Hiroki, Hattori, Shinya, Ohira, Kenji, Higuchi, Akio, Umeda, Kazuyoshi, Yamauchi, Shoma, Uno, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8693417/
https://www.ncbi.nlm.nih.gov/pubmed/34987681
http://dx.doi.org/10.1016/j.radcr.2021.11.054
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author Yokota, Hajime
Mukai, Hiroki
Hattori, Shinya
Ohira, Kenji
Higuchi, Akio
Umeda, Kazuyoshi
Yamauchi, Shoma
Uno, Takashi
author_facet Yokota, Hajime
Mukai, Hiroki
Hattori, Shinya
Ohira, Kenji
Higuchi, Akio
Umeda, Kazuyoshi
Yamauchi, Shoma
Uno, Takashi
author_sort Yokota, Hajime
collection PubMed
description Since leptomeningeal carcinomatosis is rarely observed before diagnosis of the primary cancer, its detection is often delayed. We report the case of a 60-year-old woman who presented with lung adenocarcinoma with leptomeningeal carcinomatosis. Magnetic resonance imaging showed the characteristic abnormal hyperintensity along the ventral surface of the brain stem on fluid-attenuated inversion recovery and diffusion weighted imaging. It had no contrast uptake. Based on these findings, we were able to make an early diagnosis of leptomeningeal carcinomatosis of lung adenocarcinoma. This condition was resolved after treatment with a tyrosine kinase inhibitor.
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spelling pubmed-86934172022-01-04 Band-like hyperintensity along the ventral surface of the brain stem on FLAIR and DWI in leptomeningeal carcinomatosis of lung adenocarcinoma Yokota, Hajime Mukai, Hiroki Hattori, Shinya Ohira, Kenji Higuchi, Akio Umeda, Kazuyoshi Yamauchi, Shoma Uno, Takashi Radiol Case Rep Case Report Since leptomeningeal carcinomatosis is rarely observed before diagnosis of the primary cancer, its detection is often delayed. We report the case of a 60-year-old woman who presented with lung adenocarcinoma with leptomeningeal carcinomatosis. Magnetic resonance imaging showed the characteristic abnormal hyperintensity along the ventral surface of the brain stem on fluid-attenuated inversion recovery and diffusion weighted imaging. It had no contrast uptake. Based on these findings, we were able to make an early diagnosis of leptomeningeal carcinomatosis of lung adenocarcinoma. This condition was resolved after treatment with a tyrosine kinase inhibitor. Elsevier 2021-12-16 /pmc/articles/PMC8693417/ /pubmed/34987681 http://dx.doi.org/10.1016/j.radcr.2021.11.054 Text en © 2021 The Authors. Published by Elsevier Inc. on behalf of University of Washington. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Yokota, Hajime
Mukai, Hiroki
Hattori, Shinya
Ohira, Kenji
Higuchi, Akio
Umeda, Kazuyoshi
Yamauchi, Shoma
Uno, Takashi
Band-like hyperintensity along the ventral surface of the brain stem on FLAIR and DWI in leptomeningeal carcinomatosis of lung adenocarcinoma
title Band-like hyperintensity along the ventral surface of the brain stem on FLAIR and DWI in leptomeningeal carcinomatosis of lung adenocarcinoma
title_full Band-like hyperintensity along the ventral surface of the brain stem on FLAIR and DWI in leptomeningeal carcinomatosis of lung adenocarcinoma
title_fullStr Band-like hyperintensity along the ventral surface of the brain stem on FLAIR and DWI in leptomeningeal carcinomatosis of lung adenocarcinoma
title_full_unstemmed Band-like hyperintensity along the ventral surface of the brain stem on FLAIR and DWI in leptomeningeal carcinomatosis of lung adenocarcinoma
title_short Band-like hyperintensity along the ventral surface of the brain stem on FLAIR and DWI in leptomeningeal carcinomatosis of lung adenocarcinoma
title_sort band-like hyperintensity along the ventral surface of the brain stem on flair and dwi in leptomeningeal carcinomatosis of lung adenocarcinoma
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8693417/
https://www.ncbi.nlm.nih.gov/pubmed/34987681
http://dx.doi.org/10.1016/j.radcr.2021.11.054
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