Time-resolved detection of SDS-induced conformational changes in α-synuclein by a micro-stopped-flow system

An intrinsically disordered protein, α-synuclein (αSyn), binds to negatively charged phospholipid membranes and adopts an α-helical structure. This conformational change is also induced by interaction with sodium dodecyl sulfate (SDS), which is an anionic surfactant used in previous studies to mimic...

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Detalles Bibliográficos
Autores principales: Takaramoto, Shunki, Nakasone, Yusuke, Sadakane, Kei, Maruta, Shinsaku, Terazima, Masahide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8693425/
https://www.ncbi.nlm.nih.gov/pubmed/35423687
http://dx.doi.org/10.1039/d0ra09614h

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8693425/
https://www.ncbi.nlm.nih.gov/pubmed/35423687
http://dx.doi.org/10.1039/d0ra09614h

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