Theoretical investigation on the effect of terahertz wave on Ca(2+) transport in the calcium channel

The question of whether terahertz (THz) waves can interact with ions in channels of nerve cells and cause a further reaction has attracted much attention. To answer this question, we investigate the spontaneous radiation generated by Ca(2+) moving in calcium channels and the effect of THz radiation on the transport of Ca(2+) by solving the mathematical physical model through Brownian dynamics (BD) simulations. It is obtained that the moving Ca(2+) in a calcium channel can generate electromagnetic radiation, the corresponding spectrum of which is concentrated in the THz range. Meanwhile, both the ion number in the channel and the background temperature are proved to have significant effects on the spontaneous emission spectra. The studies also show that external THz radiation can accelerate Ca(2+) transport through the ion channel. These results are expected to provide a theoretical basis for the future treatment of THz waves in the neurological field.