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Extracellular HMGB1 interacts with RAGE and promotes chemoresistance in acute leukemia cells

BACKGROUND: Nowadays, acute leukemia (AL) among children has favorable outcome, yet some of them get refractory or relapse mainly due to drug resistance. High-mobility group box 1 (HMGB1) has been proven to have a important role in drug resistance via upregulation of autophagy after chemotherapy tre...

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Detalles Bibliográficos
Autores principales:	Lai, Weixin, Li, Xinyu, Kong, Qian, Chen, Han, Li, Yunyao, Xu, Lu-Hong, Fang, Jianpei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Primary Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8693501/ https://www.ncbi.nlm.nih.gov/pubmed/34933679 http://dx.doi.org/10.1186/s12935-021-02387-9

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