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Three-dimensional, symmetrically assembled microfluidic device for lipid nanoparticle production

Sub 100 nm-sized lipid nanoparticles (LNPs) have been widely used in drug delivery systems (DDSs). The size of the LNPs is an important parameter for the DDS performance, such as biodistribution and gene silencing using siRNAs. However, the LNPs prepared by the conventional preparation method show a...

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Detalles Bibliográficos
Autores principales: Kimura, Niko, Maeki, Masatoshi, Sasaki, Kosuke, Sato, Yusuke, Ishida, Akihiko, Tani, Hirofumi, Harashima, Hideyoshi, Tokeshi, Manabu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8693528/
https://www.ncbi.nlm.nih.gov/pubmed/35424092
http://dx.doi.org/10.1039/d0ra08826a