Fast and memory-efficient mapping of short bisulfite sequencing reads using a two-letter alphabet

DNA cytosine methylation is an important epigenomic mark with a wide range of functions in many organisms. Whole genome bisulfite sequencing is the gold standard to interrogate cytosine methylation genome-wide. Algorithms used to map bisulfite-converted reads often encode the four-base DNA alphabet...

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Detalles Bibliográficos
Autores principales: de Sena Brandine, Guilherme, Smith, Andrew D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
High Throughput Sequencing Methods
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8693577/
https://www.ncbi.nlm.nih.gov/pubmed/34988438
http://dx.doi.org/10.1093/nargab/lqab115

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8693577/
https://www.ncbi.nlm.nih.gov/pubmed/34988438
http://dx.doi.org/10.1093/nargab/lqab115

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