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Fast and memory-efficient mapping of short bisulfite sequencing reads using a two-letter alphabet

DNA cytosine methylation is an important epigenomic mark with a wide range of functions in many organisms. Whole genome bisulfite sequencing is the gold standard to interrogate cytosine methylation genome-wide. Algorithms used to map bisulfite-converted reads often encode the four-base DNA alphabet...

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Detalles Bibliográficos
Autores principales:	de Sena Brandine, Guilherme, Smith, Andrew D
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2021
Materias:	High Throughput Sequencing Methods
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8693577/ https://www.ncbi.nlm.nih.gov/pubmed/34988438 http://dx.doi.org/10.1093/nargab/lqab115

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