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PCSK9 regulates the NODAL signaling pathway and cellular proliferation in hiPSCs

Proprotein convertase subtilisin kexin type 9 (PCSK9) is a key regulator of low-density lipoprotein (LDL) cholesterol metabolism and the target of lipid-lowering drugs. PCSK9 is mainly expressed in hepatocytes. Here, we show that PCSK9 is highly expressed in undifferentiated human induced pluripoten...

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Detalles Bibliográficos
Autores principales:	Roudaut, Meryl, Idriss, Salam, Caillaud, Amandine, Girardeau, Aurore, Rimbert, Antoine, Champon, Benoite, David, Amandine, Lévêque, Antoine, Arnaud, Lucie, Pichelin, Matthieu, Prieur, Xavier, Prat, Annik, Seidah, Nabil G., Zibara, Kazem, Le May, Cedric, Cariou, Bertrand, Si-Tayeb, Karim
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8693623/ https://www.ncbi.nlm.nih.gov/pubmed/34739847 http://dx.doi.org/10.1016/j.stemcr.2021.10.004

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