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Peptide modified manganese-doped iron oxide nanoparticles as a sensitive fluorescence nanosensor for non-invasive detection of trypsin activity in vitro and in vivo

Herein, a fluorescence turn-on nanosensor (MnIO@pep-FITC) has been proposed for detecting trypsin activity in vitro and in vivo through covalently immobilizing an FITC modified peptide substrate of trypsin (pep-FITC) on manganese-doped iron oxide nanoparticle (MnIO NP) surfaces via a polyethylene gl...

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Detalles Bibliográficos
Autores principales: Fu, Yu, Liu, Lin, Li, Xiaodong, Chen, Hongda, Wang, Zhenxin, Yang, Wensheng, Zhang, Hua, Zhang, Huimao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8693661/
https://www.ncbi.nlm.nih.gov/pubmed/35424166
http://dx.doi.org/10.1039/d0ra08171j

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