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Peptide modified manganese-doped iron oxide nanoparticles as a sensitive fluorescence nanosensor for non-invasive detection of trypsin activity in vitro and in vivo
Herein, a fluorescence turn-on nanosensor (MnIO@pep-FITC) has been proposed for detecting trypsin activity in vitro and in vivo through covalently immobilizing an FITC modified peptide substrate of trypsin (pep-FITC) on manganese-doped iron oxide nanoparticle (MnIO NP) surfaces via a polyethylene gl...
Autores principales: | Fu, Yu, Liu, Lin, Li, Xiaodong, Chen, Hongda, Wang, Zhenxin, Yang, Wensheng, Zhang, Hua, Zhang, Huimao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8693661/ https://www.ncbi.nlm.nih.gov/pubmed/35424166 http://dx.doi.org/10.1039/d0ra08171j |
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