Cargando…
Molnupiravir for Oral Treatment of Covid-19 in Nonhospitalized Patients
BACKGROUND: New treatments are needed to reduce the risk of progression of coronavirus disease 2019 (Covid-19). Molnupiravir is an oral, small-molecule antiviral prodrug that is active against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). METHODS: We conducted a phase 3, double-blind...
Autores principales: | Jayk Bernal, Angélica, Gomes da Silva, Monica M., Musungaie, Dany B., Kovalchuk, Evgeniy, Gonzalez, Antonio, Delos Reyes, Virginia, Martín-Quirós, Alejandro, Caraco, Yoseph, Williams-Diaz, Angela, Brown, Michelle L., Du, Jiejun, Pedley, Alison, Assaid, Christopher, Strizki, Julie, Grobler, Jay A., Shamsuddin, Hala H., Tipping, Robert, Wan, Hong, Paschke, Amanda, Butterton, Joan R., Johnson, Matthew G., De Anda, Carisa |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Massachusetts Medical Society
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8693688/ https://www.ncbi.nlm.nih.gov/pubmed/34914868 http://dx.doi.org/10.1056/NEJMoa2116044 |
Ejemplares similares
-
Molnupiravir for the treatment of COVID-19 in immunocompromised participants: efficacy, safety, and virology results from the phase 3 randomized, placebo-controlled MOVe-OUT trial
por: Johnson, Matthew G., et al.
Publicado: (2023) -
511. Treatment with Molnupiravir in the MOVe-In and MOVe-Out Clinical Trials Results in an Increase in Transition Mutations Across the SARS-CoV-2 Genome
por: Strizki, Julie, et al.
Publicado: (2021) -
543. Molnupiravir Maintains Antiviral Activity Against SARS-CoV-2 Variants In Vitro and in Early Clinical Studies
por: Grobler, Jay, et al.
Publicado: (2021) -
153. Molnupiravir Exhibits a High Barrier to the Development of SARS-CoV-2 Resistance in vitro
por: Strizki, Julie, et al.
Publicado: (2022) -
Real-World Utilization of Molnupiravir during the COVID-19 Omicron Surge in Israel
por: Weil, Clara, et al.
Publicado: (2023)