The design, synthesis, and in vitro trypanocidal and leishmanicidal activities of 1,3-thiazole and 4-thiazolidinone ester derivatives

Chagas and leishmaniasis are both neglected tropical diseases, whose inefficient therapies have made them remain the cause for millions of deaths worldwide. Given this, we synthesized 27 novel 1,3-thiazoles and 4-thiazolidinones using bioisosteric and esterification strategies to develop improved an...

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Detalles Bibliográficos
Autores principales: Haroon, Muhammad, de Barros Dias, Mabilly Cox Holanda, Santos, Aline Caroline da Silva, Pereira, Valéria Rêgo Alves, Barros Freitas, Luiz Alberto, Balbinot, Rodolfo Bento, Kaplum, Vanessa, Nakamura, Celso Vataru, Alves, Luiz Carlos, Brayner, Fábio André, Leite, Ana Cristina Lima, Akhtar, Tashfeen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8693751/
https://www.ncbi.nlm.nih.gov/pubmed/35424158
http://dx.doi.org/10.1039/d0ra06994a

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