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Virtual screening and in vitro validation of natural compound inhibitors against SARS-CoV-2 spike protein

The COVID-19 pandemic caused by the SARS-CoV-2 virus has led to a major public health burden and has resulted in millions of deaths worldwide. As effective treatments are limited, there is a significant requirement for high-throughput, low resource methods for the discovery of novel antivirals. The...

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Detalles Bibliográficos
Autores principales: Power, Helen, Wu, Jiadai, Turville, Stuart, Aggarwal, Anupriya, Valtchev, Peter, Schindeler, Aaron, Dehghani, Fariba
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8693770/
https://www.ncbi.nlm.nih.gov/pubmed/34971947
http://dx.doi.org/10.1016/j.bioorg.2021.105574