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DNA-encoded libraries (DELs): a review of on-DNA chemistries and their output

A DNA-encoded library is a collection of small molecules covalently linked to DNA that has unique information about the identity and the structure of each library member. A DNA-encoded chemical library (DEL) is broadly adopted by major pharmaceutical companies and used in numerous drug discovery pro...

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Detalles Bibliográficos
Autores principales: Shi, Ying, Wu, Yan-ran, Yu, Jian-qiang, Zhang, Wan-nian, Zhuang, Chun-lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8693808/
https://www.ncbi.nlm.nih.gov/pubmed/35424149
http://dx.doi.org/10.1039/d0ra09889b