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DNA-encoded libraries (DELs): a review of on-DNA chemistries and their output
A DNA-encoded library is a collection of small molecules covalently linked to DNA that has unique information about the identity and the structure of each library member. A DNA-encoded chemical library (DEL) is broadly adopted by major pharmaceutical companies and used in numerous drug discovery pro...
Autores principales: | Shi, Ying, Wu, Yan-ran, Yu, Jian-qiang, Zhang, Wan-nian, Zhuang, Chun-lin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8693808/ https://www.ncbi.nlm.nih.gov/pubmed/35424149 http://dx.doi.org/10.1039/d0ra09889b |
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