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SARS-CoV-2 Spike Protein Destabilizes Microvascular Homeostasis

SARS-CoV-2 infection can cause compromised respiratory function and thrombotic events. SARS-CoV-2 binds to and mediates downregulation of angiotensin converting enzyme 2 (ACE2) on cells that it infects. Theoretically, diminished enzymatic activity of ACE2 may result in increased concentrations of pr...

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Detalles Bibliográficos
Autores principales: Panigrahi, Soumya, Goswami, Tamal, Ferrari, Brian, Antonelli, Christopher J., Bazdar, Douglas A., Gilmore, Hannah, Freeman, Michael L., Lederman, Michael M., Sieg, Scott F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8693925/
https://www.ncbi.nlm.nih.gov/pubmed/34935423
http://dx.doi.org/10.1128/Spectrum.00735-21