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Two Cholesterol Recognition Amino Acid Consensus Motifs of GP64 with Uncleaved Signal Peptide Are Required for Bombyx mori Nucleopolyhedrovirus Infection

The signal peptide (SP) of integrated membrane proteins is removed cotranslationally or posttranslationally in the endoplasmic reticulum, while GP64, a membrane fusion protein of Bombyx mori nucleopolyhedrovirus (BmNPV), retains its SP in the mature protein and virion. In this study, we revealed tha...

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Detalles Bibliográficos
Autores principales: Hao, Bifang, Nan, Wenbin, Xu, Ying, Liu, Lin, Liu, Na, Huang, Jinshan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8694094/
https://www.ncbi.nlm.nih.gov/pubmed/34937190
http://dx.doi.org/10.1128/Spectrum.01725-21

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