Hypoxia Contributes to Poor Prognosis in Primary IDH-wt GBM by Inducing Tumor Cells MES-Like Transformation Trend and Inhibiting Immune Cells Activity

AIMS: To reveal the influence of hypoxia on tumor cells and immune cells in primary IDH-wt glioblastoma patients. METHODS: Single-cell RNA-seq data and bulk RNA-seq data were acquired from the Gene Expression Omnibus (GEO) and The Cancer Genome Atlas (TCGA) databases, respectively. Hypoxia status an...

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Detalles Bibliográficos
Autores principales: Xiong, Zujian, Liu, Hongwei, He, Chenqi, Li, Xuejun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8694101/
https://www.ncbi.nlm.nih.gov/pubmed/34956900
http://dx.doi.org/10.3389/fonc.2021.782043

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8694101/
https://www.ncbi.nlm.nih.gov/pubmed/34956900
http://dx.doi.org/10.3389/fonc.2021.782043

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