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Synthesis and photobiological applications of naphthalimide–benzothiazole conjugates: cytotoxicity and topoisomerase IIα inhibition

Conjugates of naphthalimide, benzothiazole, and indole moieties are synthesized that show excellent cytotoxicity against A549 (lung), MCF7 (breast), and HeLa (cervix) cancer cell lines with IC(50) values in the range of 0.14–8.59 μM. Compounds 12 and 13 substituted with ethanolamine and propargyl gr...

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Detalles Bibliográficos
Autores principales: Singh, Iqubal, Luxami, Vijay, Choudhury, Diptiman, Paul, Kamaldeep
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8694140/
https://www.ncbi.nlm.nih.gov/pubmed/35424470
http://dx.doi.org/10.1039/d1ra04148g

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