Population Pharmacokinetics and Dosing Optimization of Piperacillin-Tazobactam in Critically Ill Patients on Extracorporeal Membrane Oxygenation and the Influence of Concomitant Renal Replacement Therapy

Critical illness and extracorporeal circulation, such as extracorporeal membrane oxygenation (ECMO) and continuous renal replacement therapy (CRRT), may alter the pharmacokinetics of piperacillin-tazobactam. We aimed to develop a population pharmacokinetic model of piperacillin-tazobactam in critica...

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Detalles Bibliográficos
Autores principales: Hahn, Jongsung, Min, Kyoung Lok, Kang, Soyoung, Yang, Seungwon, Park, Min Soo, Wi, Jin, Chang, Min Jung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8694146/
https://www.ncbi.nlm.nih.gov/pubmed/34937189
http://dx.doi.org/10.1128/Spectrum.00633-21

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