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The functional role of inherited CDKN2A variants in childhood acute lymphoblastic leukemia

Genetic alterations in CDKN2A tumor suppressor gene on chromosome 9p21 confer a predisposition to childhood acute lymphoblastic leukemia (ALL). Genome-wide association studies have identified missense variants in CDKN2A associated with the development of ALL. This study systematically evaluated the...

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Detalles Bibliográficos
Autores principales: Li, Chunjie, Zhao, Xinying, He, Yingyi, Li, Ziping, Qian, Jiabi, Zhang, Li, Ye, Qian, Qiu, Fei, Lian, Peng, Qian, Maoxiang, Zhang, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8694244/
https://www.ncbi.nlm.nih.gov/pubmed/34369425
http://dx.doi.org/10.1097/FPC.0000000000000451