Discovery of phosphotyrosine-binding oligopeptides with supramolecular target selectivity

We demonstrate phage-display screening on self-assembled ligands that enables the identification of oligopeptides that selectively bind dynamic supramolecular targets over their unassembled counterparts. The concept is demonstrated through panning of a phage-display oligopeptide library against supr...

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Detalles Bibliográficos
Autores principales: Pina, Ana S., Morgado, Leonor, Duncan, Krystyna L., Carvalho, Sara, Carvalho, Henrique F., Barbosa, Arménio J. M., de P. Mariz, Beatriz, Moreira, Inês P., Kalafatovic, Daniela, Morais Faustino, Bruno M., Narang, Vishal, Wang, Tong, Pappas, Charalampos G., Ferreira, Isabel, Roque, A. Cecília A., Ulijn, Rein V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8694286/
https://www.ncbi.nlm.nih.gov/pubmed/35059169
http://dx.doi.org/10.1039/d1sc04420f

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8694286/
https://www.ncbi.nlm.nih.gov/pubmed/35059169
http://dx.doi.org/10.1039/d1sc04420f

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