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Modeling and control of an invasive mechanical ventilation system using the active disturbances rejection control structure

We propose a mandatory invasive mechanical ventilator prototype for severe COVID-19 patients with volume and pressure control operation modes. This system comprises basic pneumatic elements and sensors. Its performance is similar to commercial equipment, and it presents robustness to external distur...

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Autores principales: Almeida, David I. Rosas, Cárdenas, Armando Cantú, Fuentes, Iván Olaf Hernández, Cota, Rosa Citlalli Anguiano, León, Laura Ocotlán Orea, Martínez, David Rafael Cañez, Contreras, Angélica María Martínez
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier Ltd on behalf of ISA. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8694370/
https://www.ncbi.nlm.nih.gov/pubmed/34983734
http://dx.doi.org/10.1016/j.isatra.2021.12.021
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author Almeida, David I. Rosas
Cárdenas, Armando Cantú
Fuentes, Iván Olaf Hernández
Cota, Rosa Citlalli Anguiano
León, Laura Ocotlán Orea
Martínez, David Rafael Cañez
Contreras, Angélica María Martínez
author_facet Almeida, David I. Rosas
Cárdenas, Armando Cantú
Fuentes, Iván Olaf Hernández
Cota, Rosa Citlalli Anguiano
León, Laura Ocotlán Orea
Martínez, David Rafael Cañez
Contreras, Angélica María Martínez
author_sort Almeida, David I. Rosas
collection PubMed
description We propose a mandatory invasive mechanical ventilator prototype for severe COVID-19 patients with volume and pressure control operation modes. This system comprises basic pneumatic elements and sensors. Its performance is similar to commercial equipment, and it presents robustness to external disturbances and parametric uncertainties. To develop a control strategy, we propose a mathematical model with a variable structure that incorporates the dead zone phenomenon of the proportional valve, and considers external disturbances and parametric uncertainties. Based on this model, we propose a global control strategy that is based on pressure and flow regulation controllers, which use the active disturbances rejection control structure (ADRC). In this strategy, we propose robust state observers to estimate disturbances and the signals necessary for implementing the controllers. We illustrate the performance of the prototype and the control strategy through numerical simulations and experiments. We also compare its performance with PID controllers. These results corroborate its effectiveness and the possibility of its application in invasive mechanical ventilators with a simple structure, which can significantly help critical care of COVID-19 inpatients.
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spelling pubmed-86943702021-12-23 Modeling and control of an invasive mechanical ventilation system using the active disturbances rejection control structure Almeida, David I. Rosas Cárdenas, Armando Cantú Fuentes, Iván Olaf Hernández Cota, Rosa Citlalli Anguiano León, Laura Ocotlán Orea Martínez, David Rafael Cañez Contreras, Angélica María Martínez ISA Trans Research Article We propose a mandatory invasive mechanical ventilator prototype for severe COVID-19 patients with volume and pressure control operation modes. This system comprises basic pneumatic elements and sensors. Its performance is similar to commercial equipment, and it presents robustness to external disturbances and parametric uncertainties. To develop a control strategy, we propose a mathematical model with a variable structure that incorporates the dead zone phenomenon of the proportional valve, and considers external disturbances and parametric uncertainties. Based on this model, we propose a global control strategy that is based on pressure and flow regulation controllers, which use the active disturbances rejection control structure (ADRC). In this strategy, we propose robust state observers to estimate disturbances and the signals necessary for implementing the controllers. We illustrate the performance of the prototype and the control strategy through numerical simulations and experiments. We also compare its performance with PID controllers. These results corroborate its effectiveness and the possibility of its application in invasive mechanical ventilators with a simple structure, which can significantly help critical care of COVID-19 inpatients. Published by Elsevier Ltd on behalf of ISA. 2022-10 2021-12-22 /pmc/articles/PMC8694370/ /pubmed/34983734 http://dx.doi.org/10.1016/j.isatra.2021.12.021 Text en © 2021 Published by Elsevier Ltd on behalf of ISA. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Research Article
Almeida, David I. Rosas
Cárdenas, Armando Cantú
Fuentes, Iván Olaf Hernández
Cota, Rosa Citlalli Anguiano
León, Laura Ocotlán Orea
Martínez, David Rafael Cañez
Contreras, Angélica María Martínez
Modeling and control of an invasive mechanical ventilation system using the active disturbances rejection control structure
title Modeling and control of an invasive mechanical ventilation system using the active disturbances rejection control structure
title_full Modeling and control of an invasive mechanical ventilation system using the active disturbances rejection control structure
title_fullStr Modeling and control of an invasive mechanical ventilation system using the active disturbances rejection control structure
title_full_unstemmed Modeling and control of an invasive mechanical ventilation system using the active disturbances rejection control structure
title_short Modeling and control of an invasive mechanical ventilation system using the active disturbances rejection control structure
title_sort modeling and control of an invasive mechanical ventilation system using the active disturbances rejection control structure
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8694370/
https://www.ncbi.nlm.nih.gov/pubmed/34983734
http://dx.doi.org/10.1016/j.isatra.2021.12.021
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