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Asymmetric synthesis of N–N axially chiral compounds via organocatalytic atroposelective N-acylation

Compared with the well-developed C–C and C–N axial chirality, the asymmetric synthesis of N–N axial chirality remains elusive and challenging. Herein we report the first atroposelective N-acylation reaction of quinazolinone type benzamides with cinnamic anhydrides for the direct catalytic synthesis...

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Detalles Bibliográficos
Autores principales: Lin, Wei, Zhao, Qun, Li, Yao, Pan, Ming, Yang, Chen, Yang, Guo-Hui, Li, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8694391/
https://www.ncbi.nlm.nih.gov/pubmed/35059162
http://dx.doi.org/10.1039/d1sc05360d