Methylome inheritance and enhancer dememorization reset an epigenetic gate safeguarding embryonic programs

Marked epigenetic reprogramming is essential to convert terminally differentiated gametes to totipotent embryos. It remains puzzling why postfertilization global DNA reprogramming occurs in mammals but not in nonmammalian vertebrates. In zebrafish, global methylome inheritance is however accompanied...

Descripción completa

Detalles Bibliográficos
Autores principales: Wu, Xiaotong, Zhang, Hongmei, Zhang, Bingjie, Zhang, Yu, Wang, Qiuyan, Shen, Weimin, Wu, Xi, Li, Lijia, Xia, Weikun, Nakamura, Ryohei, Liu, Bofeng, Liu, Feng, Takeda, Hiroyuki, Meng, Anming, Xie, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8694617/
https://www.ncbi.nlm.nih.gov/pubmed/34936444
http://dx.doi.org/10.1126/sciadv.abl3858

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8694617/
https://www.ncbi.nlm.nih.gov/pubmed/34936444
http://dx.doi.org/10.1126/sciadv.abl3858

Ejemplares similares