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Loss of ATF4 leads to functional aging-like attrition of adult hematopoietic stem cells

Aging of hematopoietic stem cells (HSCs) directly contributes to dysfunction of hematopoietic and immune systems due to aging-associated alterations in HSC features. How the function of adult HSCs is regulated during aging so that relevant pathologic abnormalities may occur, however, remains incompl...

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Detalles Bibliográficos
Autores principales:	Sun, Yan, Lin, Xiaolin, Liu, Bangdong, Zhang, Yaxuan, Li, Wei, Zhang, Sheng, He, Falian, Tian, Han, Zhu, Xun, Liu, Ximeng, Wu, Jueheng, Cai, Junchao, Li, Mengfeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for the Advancement of Science 2021
Materias:	Biomedicine and Life Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8694622/ https://www.ncbi.nlm.nih.gov/pubmed/34936448 http://dx.doi.org/10.1126/sciadv.abj6877

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