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Conformational changes in the yeast mitochondrial ABC transporter Atm1 during the transport cycle

The mitochondrial inner membrane ABC transporter Atm1 exports an unknown substrate to the cytosol for iron-sulfur protein biogenesis, cellular iron regulation, and tRNA thio-modification. Mutations in the human relative ABCB7 cause the iron storage disease XLSA/A. We determined 3D structures of two...

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Detalles Bibliográficos
Autores principales:	Ellinghaus, Thomas L., Marcellino, Thomas, Srinivasan, Vasundara, Lill, Roland, Kühlbrandt, Werner
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for the Advancement of Science 2021
Materias:	Biomedicine and Life Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8694623/ https://www.ncbi.nlm.nih.gov/pubmed/34936443 http://dx.doi.org/10.1126/sciadv.abk2392

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