A regioselective C7 bromination and C7 palladium-catalyzed Suzuki–Miyaura cross-coupling arylation of 4-substituted NH-free indazoles

A direct and efficient regioselective C7-bromination of 4-substituted 1H-indazole has been achieved. Subsequently, a successful palladium-mediated Suzuki–Miyaura reaction of C7-bromo-4-substituted-1H-indazoles with boronic acids has been performed under optimized reaction conditions. A series of new...

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Detalles Bibliográficos
Autores principales: Boujdi, Khalid, El Brahmi, Nabil, Graton, Jérôme, Dubreuil, Didier, Collet, Sylvain, Mathé-Allainmat, Monique, Akssira, Mohamed, Lebreton, Jacques, El Kazzouli, Saïd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8694914/
https://www.ncbi.nlm.nih.gov/pubmed/35423195
http://dx.doi.org/10.1039/d0ra08598g

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