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Determination of naphazoline HCl, pheniramine maleate and their official impurities in eye drops and biological fluid rabbit aqueous humor by a validated LC-DAD method

A simple RP-HPLC-DAD method was developed and validated, as per the ICH guidelines, for simultaneous determination of naphazoline HCl (NPZ) & pheniramine maleate (PHN) along with three of their official impurities. Chromatographic separation was performed on a hypersil ODS column (5 mm, 250–4.6...

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Detalles Bibliográficos
Autores principales: Kelani, Khadiga M., Hegazy, Maha A., Hassan, Amal M., Tantawy, Mahmoud A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8694919/
https://www.ncbi.nlm.nih.gov/pubmed/35423192
http://dx.doi.org/10.1039/d0ra10598h

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