Novel synthesis of benzotriazolyl alkyl esters: an unprecedented CH(2) insertion

We have developed a novel method for the synthesis of benzotriazolyl alkyl esters (BAEs) from N-acylbenzotriazoles and dichloromethane (DCM) under mild conditions. This reaction is one of few examples to show the use of DCM as a C-1 surrogate in carbon–heteroatom bond formation and to highlight the...

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Detalles Bibliográficos
Autores principales: Elagawany, Mohamed, Maram, Lingaiah, Elgendy, Bahaa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8694985/
https://www.ncbi.nlm.nih.gov/pubmed/35423285
http://dx.doi.org/10.1039/d0ra10413b
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author Elagawany, Mohamed
Maram, Lingaiah
Elgendy, Bahaa
author_facet Elagawany, Mohamed
Maram, Lingaiah
Elgendy, Bahaa
author_sort Elagawany, Mohamed
collection PubMed
description We have developed a novel method for the synthesis of benzotriazolyl alkyl esters (BAEs) from N-acylbenzotriazoles and dichloromethane (DCM) under mild conditions. This reaction is one of few examples to show the use of DCM as a C-1 surrogate in carbon–heteroatom bond formation and to highlight the versatility of using DCM as a methylene building block.
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spelling pubmed-86949852022-04-13 Novel synthesis of benzotriazolyl alkyl esters: an unprecedented CH(2) insertion Elagawany, Mohamed Maram, Lingaiah Elgendy, Bahaa RSC Adv Chemistry We have developed a novel method for the synthesis of benzotriazolyl alkyl esters (BAEs) from N-acylbenzotriazoles and dichloromethane (DCM) under mild conditions. This reaction is one of few examples to show the use of DCM as a C-1 surrogate in carbon–heteroatom bond formation and to highlight the versatility of using DCM as a methylene building block. The Royal Society of Chemistry 2021-02-17 /pmc/articles/PMC8694985/ /pubmed/35423285 http://dx.doi.org/10.1039/d0ra10413b Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by/3.0/
spellingShingle Chemistry
Elagawany, Mohamed
Maram, Lingaiah
Elgendy, Bahaa
Novel synthesis of benzotriazolyl alkyl esters: an unprecedented CH(2) insertion
title Novel synthesis of benzotriazolyl alkyl esters: an unprecedented CH(2) insertion
title_full Novel synthesis of benzotriazolyl alkyl esters: an unprecedented CH(2) insertion
title_fullStr Novel synthesis of benzotriazolyl alkyl esters: an unprecedented CH(2) insertion
title_full_unstemmed Novel synthesis of benzotriazolyl alkyl esters: an unprecedented CH(2) insertion
title_short Novel synthesis of benzotriazolyl alkyl esters: an unprecedented CH(2) insertion
title_sort novel synthesis of benzotriazolyl alkyl esters: an unprecedented ch(2) insertion
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8694985/
https://www.ncbi.nlm.nih.gov/pubmed/35423285
http://dx.doi.org/10.1039/d0ra10413b
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AT maramlingaiah novelsynthesisofbenzotriazolylalkylestersanunprecedentedch2insertion
AT elgendybahaa novelsynthesisofbenzotriazolylalkylestersanunprecedentedch2insertion

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