Inversion kinetics of some E/Z 3-(benzylidene)-2-oxo-indoline derivatives and their in silico CDK2 docking studies

The structure-based design of some CDK2 inhibitors with a 3-(benzylidene)indolin-2-one scaffold as potential anticancer agents was realized. Target compounds were obtained as E/Z mixtures and were resolved to corresponding E- and Z-diastereomers. In silico studies using MOE 2019.01 software revealed...

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Detalles Bibliográficos
Autores principales: Mansour, Hany S., Abd El-wahab, Hend A. A., Ali, Ahmed M., Aboul-Fadl, Tarek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8695066/
https://www.ncbi.nlm.nih.gov/pubmed/35423292
http://dx.doi.org/10.1039/d0ra10672k

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8695066/
https://www.ncbi.nlm.nih.gov/pubmed/35423292
http://dx.doi.org/10.1039/d0ra10672k

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