Cargando…
Chondrocyte-derived Exosomal miR-195 Inhibits Osteosarcoma Cell Proliferation and Anti-Apoptotic by Targeting KIF4A in vitro and in vivo
BACKGROUND: Osteosarcoma (OS) is a primary malignant tumor of the bone that occurs in adolescents and is characterized by a young age at onset, high malignancy, high rate of metastasis, and poor prognosis. However, the factors influencing disease progression and prognosis remain unclear. METHODS: In...
Autores principales: | Lu, Yao, Cao, Gaolu, Lan, Haiying, Liao, Hua, Hu, Yaqiong, Feng, Haihua, Liu, Xiaojian, Huang, Panpan |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Neoplasia Press
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8695354/ https://www.ncbi.nlm.nih.gov/pubmed/34952333 http://dx.doi.org/10.1016/j.tranon.2021.101289 |
Ejemplares similares
-
Decrease of miR-195 Promotes Chondrocytes Proliferation and Maintenance of Chondrogenic Phenotype via Targeting FGF-18 Pathway
por: Wang, Yong, et al.
Publicado: (2017) -
Decreased expression of miR-195 mediated by hypermethylation promotes osteosarcoma
por: Sun, Tianhao, et al.
Publicado: (2022) -
The FBXO32/ATR/ATM axis acts as a molecular switch to control the sensitivity of osteosarcoma cells to irradiation through its regulation of EXO1 expression: FBXO32/ATR/ATM/EXO1 axis induces OS cells to anti-radiotherapy
por: Lu, Yao, et al.
Publicado: (2023) -
MicroRNA profiling identifies MiR-195 suppresses osteosarcoma cell metastasis by targeting CCND1
por: Han, Kang, et al.
Publicado: (2015) -
CircKIF4A enhances osteosarcoma proliferation and metastasis by sponging MiR-515-5p and upregulating SLC7A11
por: He, Pan, et al.
Publicado: (2022)