NDRG1 Activity in Fat Depots Is Associated With Type 2 Diabetes and Impaired Incretin Profile in Patients With Morbid Obesity

OBJECTIVE: We aimed to investigate insulin-, mTOR- and SGK1-dependent signaling basal states in morbidly obese patients’ fat. We analyzed the correlation between the signaling activity, carbohydrate metabolism, and incretin profiles of patients. METHODS: The omental and subcutaneous fat was obtained...

Descripción completa

Detalles Bibliográficos
Autores principales: Stafeev, Iurii, Sklyanik, Igor, Mamontova, Elizaveta, Michurina, Svetlana, Shestakova, Ekaterina, Yah’yaev, Kamil, Yurasov, Anatoliy, Masnikov, Denis, Sineokaya, Maria, Ratner, Elizaveta, Vorotnikov, Alexander, Menshikov, Mikhail, Parfyonova, Yelena, Shestakova, Marina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8695674/
https://www.ncbi.nlm.nih.gov/pubmed/34956089
http://dx.doi.org/10.3389/fendo.2021.777589

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8695674/
https://www.ncbi.nlm.nih.gov/pubmed/34956089
http://dx.doi.org/10.3389/fendo.2021.777589

Ejemplares similares