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NDRG1 Activity in Fat Depots Is Associated With Type 2 Diabetes and Impaired Incretin Profile in Patients With Morbid Obesity
OBJECTIVE: We aimed to investigate insulin-, mTOR- and SGK1-dependent signaling basal states in morbidly obese patients’ fat. We analyzed the correlation between the signaling activity, carbohydrate metabolism, and incretin profiles of patients. METHODS: The omental and subcutaneous fat was obtained...
Autores principales: | Stafeev, Iurii, Sklyanik, Igor, Mamontova, Elizaveta, Michurina, Svetlana, Shestakova, Ekaterina, Yah’yaev, Kamil, Yurasov, Anatoliy, Masnikov, Denis, Sineokaya, Maria, Ratner, Elizaveta, Vorotnikov, Alexander, Menshikov, Mikhail, Parfyonova, Yelena, Shestakova, Marina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8695674/ https://www.ncbi.nlm.nih.gov/pubmed/34956089 http://dx.doi.org/10.3389/fendo.2021.777589 |
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