Cargando…
Imaging Manifestations of Intrahepatic Reactive Lymphoid Hyperplasia: A Case Report and Literature Review
Reactive lymphoid hyperplasia (RLH) of the liver is a rare benign disease. This article describes a 77-year-old female patient with RLH of the liver. The patient was admitted to the hospital due to atrial fibrillation. A liver tumor was incidentally found during abdominal enhanced CT. Further magnet...
Autores principales: | , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8695756/ https://www.ncbi.nlm.nih.gov/pubmed/34956855 http://dx.doi.org/10.3389/fonc.2021.694934 |
_version_ | 1784619649489436672 |
---|---|
author | Zhang, Bingqian Zou, Mingyue Lu, Zengxin Mao, Haijia Huang, Ya’nan Liu, Fang Zhao, Zhenhua |
author_facet | Zhang, Bingqian Zou, Mingyue Lu, Zengxin Mao, Haijia Huang, Ya’nan Liu, Fang Zhao, Zhenhua |
author_sort | Zhang, Bingqian |
collection | PubMed |
description | Reactive lymphoid hyperplasia (RLH) of the liver is a rare benign disease. This article describes a 77-year-old female patient with RLH of the liver. The patient was admitted to the hospital due to atrial fibrillation. A liver tumor was incidentally found during abdominal enhanced CT. Further magnetic resonance imaging (MRI) and PET/CT showed four lesions in the liver. The imaging findings suggested hepatocellular carcinoma (HCC), but it was not consistent that the patient had no history of liver cirrhosis and hepatitis, and a variety of tumor markers were within the normal range. The largest lesion was surgically removed and microscopically diagnosed as RLH of the liver. The pathology included a large number of reactive hyperplastic lymphoid follicles. Immunohistochemical examination showed that the infiltrating lymphocytes were polyclonal. The authors believe that the perinodular enhancement on MRI, the obvious limitation of diffusion on DWI, the insignificant increase of SUVmax on PET-CT delayed phase, and the support of clinical data can help distinguish liver RLH from lymphoma and HCC. |
format | Online Article Text |
id | pubmed-8695756 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-86957562021-12-24 Imaging Manifestations of Intrahepatic Reactive Lymphoid Hyperplasia: A Case Report and Literature Review Zhang, Bingqian Zou, Mingyue Lu, Zengxin Mao, Haijia Huang, Ya’nan Liu, Fang Zhao, Zhenhua Front Oncol Oncology Reactive lymphoid hyperplasia (RLH) of the liver is a rare benign disease. This article describes a 77-year-old female patient with RLH of the liver. The patient was admitted to the hospital due to atrial fibrillation. A liver tumor was incidentally found during abdominal enhanced CT. Further magnetic resonance imaging (MRI) and PET/CT showed four lesions in the liver. The imaging findings suggested hepatocellular carcinoma (HCC), but it was not consistent that the patient had no history of liver cirrhosis and hepatitis, and a variety of tumor markers were within the normal range. The largest lesion was surgically removed and microscopically diagnosed as RLH of the liver. The pathology included a large number of reactive hyperplastic lymphoid follicles. Immunohistochemical examination showed that the infiltrating lymphocytes were polyclonal. The authors believe that the perinodular enhancement on MRI, the obvious limitation of diffusion on DWI, the insignificant increase of SUVmax on PET-CT delayed phase, and the support of clinical data can help distinguish liver RLH from lymphoma and HCC. Frontiers Media S.A. 2021-12-09 /pmc/articles/PMC8695756/ /pubmed/34956855 http://dx.doi.org/10.3389/fonc.2021.694934 Text en Copyright © 2021 Zhang, Zou, Lu, Mao, Huang, Liu and Zhao https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Oncology Zhang, Bingqian Zou, Mingyue Lu, Zengxin Mao, Haijia Huang, Ya’nan Liu, Fang Zhao, Zhenhua Imaging Manifestations of Intrahepatic Reactive Lymphoid Hyperplasia: A Case Report and Literature Review |
title | Imaging Manifestations of Intrahepatic Reactive Lymphoid Hyperplasia: A Case Report and Literature Review |
title_full | Imaging Manifestations of Intrahepatic Reactive Lymphoid Hyperplasia: A Case Report and Literature Review |
title_fullStr | Imaging Manifestations of Intrahepatic Reactive Lymphoid Hyperplasia: A Case Report and Literature Review |
title_full_unstemmed | Imaging Manifestations of Intrahepatic Reactive Lymphoid Hyperplasia: A Case Report and Literature Review |
title_short | Imaging Manifestations of Intrahepatic Reactive Lymphoid Hyperplasia: A Case Report and Literature Review |
title_sort | imaging manifestations of intrahepatic reactive lymphoid hyperplasia: a case report and literature review |
topic | Oncology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8695756/ https://www.ncbi.nlm.nih.gov/pubmed/34956855 http://dx.doi.org/10.3389/fonc.2021.694934 |
work_keys_str_mv | AT zhangbingqian imagingmanifestationsofintrahepaticreactivelymphoidhyperplasiaacasereportandliteraturereview AT zoumingyue imagingmanifestationsofintrahepaticreactivelymphoidhyperplasiaacasereportandliteraturereview AT luzengxin imagingmanifestationsofintrahepaticreactivelymphoidhyperplasiaacasereportandliteraturereview AT maohaijia imagingmanifestationsofintrahepaticreactivelymphoidhyperplasiaacasereportandliteraturereview AT huangyanan imagingmanifestationsofintrahepaticreactivelymphoidhyperplasiaacasereportandliteraturereview AT liufang imagingmanifestationsofintrahepaticreactivelymphoidhyperplasiaacasereportandliteraturereview AT zhaozhenhua imagingmanifestationsofintrahepaticreactivelymphoidhyperplasiaacasereportandliteraturereview |