Cargando…

α-Aminoazoles/azines: key reaction partners for multicomponent reactions

Aromatic α-aminoazaheterocycles are the focus of significant investigations and exploration by researchers owing to their key role in diverse biological and physiological processes. The existence of their derivatives in numerous drugs and alkaloids is due to their heterocyclic nitrogenous nature. Th...

Descripción completa

Detalles Bibliográficos
Autores principales: Imtiaz, Shah, Ahmad war, Jahangir, Banoo, Syqa, khan, Sarfaraz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8695948/
https://www.ncbi.nlm.nih.gov/pubmed/35423648
http://dx.doi.org/10.1039/d1ra00392e
_version_ 1784619695472640000
author Imtiaz, Shah
Ahmad war, Jahangir
Banoo, Syqa
khan, Sarfaraz
author_facet Imtiaz, Shah
Ahmad war, Jahangir
Banoo, Syqa
khan, Sarfaraz
author_sort Imtiaz, Shah
collection PubMed
description Aromatic α-aminoazaheterocycles are the focus of significant investigations and exploration by researchers owing to their key role in diverse biological and physiological processes. The existence of their derivatives in numerous drugs and alkaloids is due to their heterocyclic nitrogenous nature. Therefore, the synthesis of a structurally diverse range of their derivatives through simple and convenient methods represents a vital field of synthetic organic chemistry. Multicomponent reactions (MCRs) provide a platform to introduce desirable structure diversity and complexity into a molecule in a single operation with a significant reduction in the use of harmful organic waste, and hence have attracted particular attention as an excellent tool to access these derivatives. This review covers the advances made from 2010 to the beginning of 2020 in terms of the utilization of α-aminoazaheterocycles as synthetic precursors in MCRs.
format Online
Article
Text
id pubmed-8695948
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher The Royal Society of Chemistry
record_format MEDLINE/PubMed
spelling pubmed-86959482022-04-13 α-Aminoazoles/azines: key reaction partners for multicomponent reactions Imtiaz, Shah Ahmad war, Jahangir Banoo, Syqa khan, Sarfaraz RSC Adv Chemistry Aromatic α-aminoazaheterocycles are the focus of significant investigations and exploration by researchers owing to their key role in diverse biological and physiological processes. The existence of their derivatives in numerous drugs and alkaloids is due to their heterocyclic nitrogenous nature. Therefore, the synthesis of a structurally diverse range of their derivatives through simple and convenient methods represents a vital field of synthetic organic chemistry. Multicomponent reactions (MCRs) provide a platform to introduce desirable structure diversity and complexity into a molecule in a single operation with a significant reduction in the use of harmful organic waste, and hence have attracted particular attention as an excellent tool to access these derivatives. This review covers the advances made from 2010 to the beginning of 2020 in terms of the utilization of α-aminoazaheterocycles as synthetic precursors in MCRs. The Royal Society of Chemistry 2021-03-16 /pmc/articles/PMC8695948/ /pubmed/35423648 http://dx.doi.org/10.1039/d1ra00392e Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by-nc/3.0/
spellingShingle Chemistry
Imtiaz, Shah
Ahmad war, Jahangir
Banoo, Syqa
khan, Sarfaraz
α-Aminoazoles/azines: key reaction partners for multicomponent reactions
title α-Aminoazoles/azines: key reaction partners for multicomponent reactions
title_full α-Aminoazoles/azines: key reaction partners for multicomponent reactions
title_fullStr α-Aminoazoles/azines: key reaction partners for multicomponent reactions
title_full_unstemmed α-Aminoazoles/azines: key reaction partners for multicomponent reactions
title_short α-Aminoazoles/azines: key reaction partners for multicomponent reactions
title_sort α-aminoazoles/azines: key reaction partners for multicomponent reactions
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8695948/
https://www.ncbi.nlm.nih.gov/pubmed/35423648
http://dx.doi.org/10.1039/d1ra00392e
work_keys_str_mv AT imtiazshah aaminoazolesazineskeyreactionpartnersformulticomponentreactions
AT ahmadwarjahangir aaminoazolesazineskeyreactionpartnersformulticomponentreactions
AT banoosyqa aaminoazolesazineskeyreactionpartnersformulticomponentreactions
AT khansarfaraz aaminoazolesazineskeyreactionpartnersformulticomponentreactions