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Receptor Interacting Protein Kinase Pathways Regulate Innate B Cell Developmental Checkpoints But Not Effector Function in Mice

Mutations in the scaffolding domain of Receptor Interacting Protein kinases (RIP) underlie the recently described human autoimmune syndrome, CRIA, characterized by lymphadenopathy, splenomegaly, and autoantibody production. While disease mechanisms for CRIA remain undescribed, RIP kinases work toget...

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Detalles Bibliográficos
Autores principales:	Parthasarathy, Raksha, Hägglöf, Thomas, Hadley, Jason T., McLennan, Alexandra, Mattke, Aiden, Dudley, Elizabeth A., Kumagai, Abigail, Dong, Lily Q., Leadbetter, Elizabeth A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8696004/ https://www.ncbi.nlm.nih.gov/pubmed/34956189 http://dx.doi.org/10.3389/fimmu.2021.758407

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