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Cepharanthine Suppresses Herpes Simplex Virus Type 1 Replication Through the Downregulation of the PI3K/Akt and p38 MAPK Signaling Pathways
Cepharanthine (CEP) is a naturally occurring isoquinoline alkaloid extracted from Stephania cepharantha Hayata. Although its underlying molecular mechanism is not fully understood, this compound is reported as a promising antiviral drug. In the present study, we explore the anti-HSV-1 effects and th...
Autores principales: | Liu, Yao, Chen, Li, Liu, Wenjun, Li, Dan, Zeng, Jiuseng, Tang, Qiong, Zhang, Yuexin, Luan, Fei, Zeng, Nan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8696181/ https://www.ncbi.nlm.nih.gov/pubmed/34956164 http://dx.doi.org/10.3389/fmicb.2021.795756 |
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