Novel strategy for disease risk prediction incorporating predicted gene expression and DNA methylation data: a multi‐phased study of prostate cancer

BACKGROUND: DNA methylation and gene expression are known to play important roles in the etiology of human diseases such as prostate cancer (PCa). However, it has not yet been possible to incorporate information of DNA methylation and gene expression into polygenic risk scores (PRSs). Here, we aimed...

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Detalles Bibliográficos
Autores principales: Wu, Chong, Zhu, Jingjing, King, Austin, Tong, Xiaoran, Lu, Qing, Park, Jong Y., Wang, Liang, Gao, Guimin, Deng, Hong‐Wen, Yang, Yaohua, Knudsen, Karen E., Rebbeck, Timothy R., Long, Jirong, Zheng, Wei, Pan, Wei, Conti, David V., Haiman, Christopher A, Wu, Lang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8696216/
https://www.ncbi.nlm.nih.gov/pubmed/34520132
http://dx.doi.org/10.1002/cac2.12205

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