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From salt to hypertension, what is missed?

Excess salt intake is viewed as a major contributor to hypertension and cardiovascular disease, and dietary salt restriction is broadly recommended by public health guidelines. However, individuals can have widely varying physiological responses to salt intake, and a tailored approach to evaluation...

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Detalles Bibliográficos
Autores principales: Ma, Zhiyi, Hummel, Scott L., Sun, Ningling, Chen, Yuanyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8696232/
https://www.ncbi.nlm.nih.gov/pubmed/34846798
http://dx.doi.org/10.1111/jch.14402
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author Ma, Zhiyi
Hummel, Scott L.
Sun, Ningling
Chen, Yuanyuan
author_facet Ma, Zhiyi
Hummel, Scott L.
Sun, Ningling
Chen, Yuanyuan
author_sort Ma, Zhiyi
collection PubMed
description Excess salt intake is viewed as a major contributor to hypertension and cardiovascular disease, and dietary salt restriction is broadly recommended by public health guidelines. However, individuals can have widely varying physiological responses to salt intake, and a tailored approach to evaluation and intervention may be needed. The traditional sodium related concepts are challenging to assess clinically for two reasons: (1) spot and 24‐hour urine sodium are frequently used to evaluate salt intake, but are more suitable for population study, and (2) some adverse effects of salt may be blood pressure‐independent. In recent years, previously unknown mechanisms of sodium absorption and storage have been discovered. This review will outline the limitations of current methods to assess sodium balance and discuss new potential evaluation methods and treatment targets.
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spelling pubmed-86962322021-12-23 From salt to hypertension, what is missed? Ma, Zhiyi Hummel, Scott L. Sun, Ningling Chen, Yuanyuan J Clin Hypertens (Greenwich) Review Excess salt intake is viewed as a major contributor to hypertension and cardiovascular disease, and dietary salt restriction is broadly recommended by public health guidelines. However, individuals can have widely varying physiological responses to salt intake, and a tailored approach to evaluation and intervention may be needed. The traditional sodium related concepts are challenging to assess clinically for two reasons: (1) spot and 24‐hour urine sodium are frequently used to evaluate salt intake, but are more suitable for population study, and (2) some adverse effects of salt may be blood pressure‐independent. In recent years, previously unknown mechanisms of sodium absorption and storage have been discovered. This review will outline the limitations of current methods to assess sodium balance and discuss new potential evaluation methods and treatment targets. John Wiley and Sons Inc. 2021-11-30 /pmc/articles/PMC8696232/ /pubmed/34846798 http://dx.doi.org/10.1111/jch.14402 Text en © 2021 The Authors. The Journal of Clinical Hypertension published by Wiley Periodicals LLC https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review
Ma, Zhiyi
Hummel, Scott L.
Sun, Ningling
Chen, Yuanyuan
From salt to hypertension, what is missed?
title From salt to hypertension, what is missed?
title_full From salt to hypertension, what is missed?
title_fullStr From salt to hypertension, what is missed?
title_full_unstemmed From salt to hypertension, what is missed?
title_short From salt to hypertension, what is missed?
title_sort from salt to hypertension, what is missed?
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8696232/
https://www.ncbi.nlm.nih.gov/pubmed/34846798
http://dx.doi.org/10.1111/jch.14402
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