APOE ε4 associates with increased risk of severe COVID-19, cerebral microhaemorrhages and post-COVID mental fatigue: a Finnish biobank, autopsy and clinical study

Apolipoprotein E ε4 allele (APOE4) has been shown to associate with increased susceptibility to SARS-CoV-2 infection and COVID-19 mortality in some previous genetic studies, but information on the role of APOE4 on the underlying pathology and parallel clinical manifestations is scarce. Here we studi...

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Detalles Bibliográficos
Autores principales: Kurki, Samu N., Kantonen, Jonas, Kaivola, Karri, Hokkanen, Laura, Mäyränpää, Mikko I., Puttonen, Henri, Martola, Juha, Pöyhönen, Minna, Kero, Mia, Tuimala, Jarno, Carpén, Olli, Kantele, Anu, Vapalahti, Olli, Tiainen, Marjaana, Tienari, Pentti J., Kaila, Kai, Hästbacka, Johanna, Myllykangas, Liisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8696243/
https://www.ncbi.nlm.nih.gov/pubmed/34949230
http://dx.doi.org/10.1186/s40478-021-01302-7

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