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Vincristine-Induced Peripheral Neuropathy in Childhood Acute Lymphoblastic Leukemia: Genetic Variation as a Potential Risk Factor

Vincristine (VCR) is the first-line chemotherapeutic medication often co-administered with other drugs to treat childhood acute lymphoblastic leukemia. Dose-dependent neurotoxicity is the main factor restricting VCR’s clinical application. VCR-induced peripheral neuropathy (VIPN) sometimes results i...

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Detalles Bibliográficos
Autores principales: Yang, Qing-Yan, Hu, Ya-Hui, Guo, Hong-Li, Xia, Ying, Zhang, Yong, Fang, Wei-Rong, Li, Yun-Man, Xu, Jing, Chen, Feng, Wang, Yong-Ren, Wang, Teng-Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8696478/
https://www.ncbi.nlm.nih.gov/pubmed/34955843
http://dx.doi.org/10.3389/fphar.2021.771487