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Erythrocytes increase endogenous sphingosine 1-phosphate levels as an adaptive response to SARS-CoV-2 infection

Low plasma levels of the signaling lipid metabolite sphingosine 1-phosphate (S1P) are associated with disrupted endothelial cell (EC) barriers, lymphopenia and reduced responsivity to hypoxia. Total S1P levels were also reduced in 23 critically ill patients with coronavirus disease 2019 (COVID-19),...

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Detalles Bibliográficos
Autores principales:	Winkler, Martin Sebastian, Claus, Ralf Alexander, Schilder, Mareike, Pöhlmann, Stefan, Coldewey, Sina M., Grundmann, Julian, Fricke, Torben, Moerer, Onnen, Meissner, Konrad, Bauer, Michael, Hofmann-Winkler, Heike, Gräler, Markus H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Portland Press Ltd. 2021
Materias:	Immunology & Inflammation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8696489/ https://www.ncbi.nlm.nih.gov/pubmed/34878105 http://dx.doi.org/10.1042/CS20210666

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