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Inorganic process for wet silica-doping of calcium phosphate
Silica is not only a biocompatible trace element but also an essential element for bone formation and metabolism. Therefore, it is often doped into bioceramics such as calcium phosphate and calcium carbonate for enhancing biomaterial ability. Heretofore, organic silica materials are employed as sili...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8696845/ https://www.ncbi.nlm.nih.gov/pubmed/35423780 http://dx.doi.org/10.1039/d1ra00288k |
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author | Sugiura, Yuki Niitsu, Kodai Saito, Yasuko Endo, Takashi Horie, Masanori |
author_facet | Sugiura, Yuki Niitsu, Kodai Saito, Yasuko Endo, Takashi Horie, Masanori |
author_sort | Sugiura, Yuki |
collection | PubMed |
description | Silica is not only a biocompatible trace element but also an essential element for bone formation and metabolism. Therefore, it is often doped into bioceramics such as calcium phosphate and calcium carbonate for enhancing biomaterial ability. Heretofore, organic silica materials are employed as silica sources, but the residual organic matter is a significant drawback in biomaterial applications. Therefore, in this study, we introduce a one-pot inorganic synthesis method for the formation of silica-doped octacalcium phosphate (OCP) using Na(2)SiO(3) as the silica source. Silica was intercalated into the OCP unit lattice, replacing its hydrous layer structure, and then a layer-by-layer structure of apatite and silica was formed. Furthermore, by immersing the fabricated silica-doped OCP into suitable solutions, both silica-doped hydroxyapatite and carbonate apatite were fabricated through a one-step inorganic processes. |
format | Online Article Text |
id | pubmed-8696845 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | The Royal Society of Chemistry |
record_format | MEDLINE/PubMed |
spelling | pubmed-86968452022-04-13 Inorganic process for wet silica-doping of calcium phosphate Sugiura, Yuki Niitsu, Kodai Saito, Yasuko Endo, Takashi Horie, Masanori RSC Adv Chemistry Silica is not only a biocompatible trace element but also an essential element for bone formation and metabolism. Therefore, it is often doped into bioceramics such as calcium phosphate and calcium carbonate for enhancing biomaterial ability. Heretofore, organic silica materials are employed as silica sources, but the residual organic matter is a significant drawback in biomaterial applications. Therefore, in this study, we introduce a one-pot inorganic synthesis method for the formation of silica-doped octacalcium phosphate (OCP) using Na(2)SiO(3) as the silica source. Silica was intercalated into the OCP unit lattice, replacing its hydrous layer structure, and then a layer-by-layer structure of apatite and silica was formed. Furthermore, by immersing the fabricated silica-doped OCP into suitable solutions, both silica-doped hydroxyapatite and carbonate apatite were fabricated through a one-step inorganic processes. The Royal Society of Chemistry 2021-03-29 /pmc/articles/PMC8696845/ /pubmed/35423780 http://dx.doi.org/10.1039/d1ra00288k Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by/3.0/ |
spellingShingle | Chemistry Sugiura, Yuki Niitsu, Kodai Saito, Yasuko Endo, Takashi Horie, Masanori Inorganic process for wet silica-doping of calcium phosphate |
title | Inorganic process for wet silica-doping of calcium phosphate |
title_full | Inorganic process for wet silica-doping of calcium phosphate |
title_fullStr | Inorganic process for wet silica-doping of calcium phosphate |
title_full_unstemmed | Inorganic process for wet silica-doping of calcium phosphate |
title_short | Inorganic process for wet silica-doping of calcium phosphate |
title_sort | inorganic process for wet silica-doping of calcium phosphate |
topic | Chemistry |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8696845/ https://www.ncbi.nlm.nih.gov/pubmed/35423780 http://dx.doi.org/10.1039/d1ra00288k |
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