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An algorithm for the direct estimation of the parameters of the SIR epidemic model from the I(t) dynamics

The discrete SIR (Susceptible–Infected–Recovered) model is used in many studies to model the evolution of epidemics. Here, we consider one of its dynamics—the exponential decrease in infected cases I(t). By considering only the I(t) dynamics, we extract three parameters: the exponent of the initial...

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Autor principal: Schmitt, François G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8696977/
https://www.ncbi.nlm.nih.gov/pubmed/34961835
http://dx.doi.org/10.1140/epjp/s13360-021-02237-7
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author Schmitt, François G.
author_facet Schmitt, François G.
author_sort Schmitt, François G.
collection PubMed
description The discrete SIR (Susceptible–Infected–Recovered) model is used in many studies to model the evolution of epidemics. Here, we consider one of its dynamics—the exponential decrease in infected cases I(t). By considering only the I(t) dynamics, we extract three parameters: the exponent of the initial exponential increase [Formula: see text] ; the maximum value [Formula: see text] ; and the exponent of the final decrease [Formula: see text] . From these three parameters, we show mathematically how to extract all relevant parameters of the SIR model. We test this procedure on numerical data and then apply the methodology to real data received from the COVID-19 situation in France. We conclude that, based on the hospitalized data and the ICU (Intensive Care Unit) cases, two exponentials are found, for the initial increase and the decrease in I(t). The parameters found are larger than reported in the literature, and they are associated with a susceptible population which is limited to a sub-sample of the total population. This may be due to the fact that the SIR model cannot be applied to the covid-19 case, due to its strong hypotheses such as mixing of all the population, or also to the fact that the parameters have changed over time, due to the political initiatives such as social distanciation and lockdown.
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spelling pubmed-86969772021-12-23 An algorithm for the direct estimation of the parameters of the SIR epidemic model from the I(t) dynamics Schmitt, François G. Eur Phys J Plus Regular Article The discrete SIR (Susceptible–Infected–Recovered) model is used in many studies to model the evolution of epidemics. Here, we consider one of its dynamics—the exponential decrease in infected cases I(t). By considering only the I(t) dynamics, we extract three parameters: the exponent of the initial exponential increase [Formula: see text] ; the maximum value [Formula: see text] ; and the exponent of the final decrease [Formula: see text] . From these three parameters, we show mathematically how to extract all relevant parameters of the SIR model. We test this procedure on numerical data and then apply the methodology to real data received from the COVID-19 situation in France. We conclude that, based on the hospitalized data and the ICU (Intensive Care Unit) cases, two exponentials are found, for the initial increase and the decrease in I(t). The parameters found are larger than reported in the literature, and they are associated with a susceptible population which is limited to a sub-sample of the total population. This may be due to the fact that the SIR model cannot be applied to the covid-19 case, due to its strong hypotheses such as mixing of all the population, or also to the fact that the parameters have changed over time, due to the political initiatives such as social distanciation and lockdown. Springer Berlin Heidelberg 2021-12-23 2022 /pmc/articles/PMC8696977/ /pubmed/34961835 http://dx.doi.org/10.1140/epjp/s13360-021-02237-7 Text en © The Author(s), under exclusive licence to Società Italiana di Fisica and Springer-Verlag GmbH Germany, part of Springer Nature 2021 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Regular Article
Schmitt, François G.
An algorithm for the direct estimation of the parameters of the SIR epidemic model from the I(t) dynamics
title An algorithm for the direct estimation of the parameters of the SIR epidemic model from the I(t) dynamics
title_full An algorithm for the direct estimation of the parameters of the SIR epidemic model from the I(t) dynamics
title_fullStr An algorithm for the direct estimation of the parameters of the SIR epidemic model from the I(t) dynamics
title_full_unstemmed An algorithm for the direct estimation of the parameters of the SIR epidemic model from the I(t) dynamics
title_short An algorithm for the direct estimation of the parameters of the SIR epidemic model from the I(t) dynamics
title_sort algorithm for the direct estimation of the parameters of the sir epidemic model from the i(t) dynamics
topic Regular Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8696977/
https://www.ncbi.nlm.nih.gov/pubmed/34961835
http://dx.doi.org/10.1140/epjp/s13360-021-02237-7
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